Couple things I noticed after acquiring my new Mac Book Pro Retina:
The android emulator doesn't play nice with the new pixel density. This is outlined here (https://jira.appcelerator.org/browse/TIMOB-9892) and the best workaround is to use SetResX menu bar app to combat it which will turn off your high resolution display. Download SetResX here (http://www.sendspace.com/file/mef6sk) and be sure to hit the Download link and not the ads.
Titanium Studio is not configured to run in Retina Display mode, but it will. If you modify the info.plist file (/Applications/Titanium Studio/TitaniumStudio.app/Contents/Info.plist) by adding a row 'High Resolution Capable' to true the IDE will look much better when it opens. After modifying the plist you'll need to move the TitaniumStudio.app out of the directory and then back in to force the OS to flush the plist settings. Another option is to logout and back in to your OS account.
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